Edmund R. Burke, has written many books on cycling and has been involved in the science of the sport for decades. In a recent article, Burke restates what I've said on this blog before as he says that as long as there's money (in cycling) there will be fraud (in the form of doping).
Burke's article is written like an analysis of strategic reasoning by auditors in that he explains how the dopers are one step ahead of the doping tests. He even explains some methods that cyclists have purportedly used to avoid detection.
He also speculates as to future methods that will be even harder to detect including gene therapy. Some of these methods are quite extreme and crude and not for the faint of heart. Similarly, some methods that corporate executives such as Barrie Minkow at ZZZBest or Ponzi schemers such as Bernie Madoff used to hide their fraud were also quite extreme and perhaps even a bit crude.