Showing posts with label blood transfusions. Show all posts
Showing posts with label blood transfusions. Show all posts

Wednesday, October 6, 2010

Lance Armstrong Investigation: Results of New Doping Test will be Crucial

If you've been following the Alberto Contador investigation, you've read that a new doping test has quietly been in development to catch athletes doing blood transfusions. The test is designed to look for signs of transfusions by detecting high amounts of plastic metabolites in urine and blood. Apparently, similar tests have been used for our food supply for some time but now it is being applied to look for blood doping in cyclists. The test has not been approved by WADA yet but the scientists working on it say they are close to establishing the cutoff for evidence that a blood transfusion was used.

While it is clear that Alberto's levels of plastic in his urine probably spell doom to his steak story, it may not be as clear what this test has to do with Lance Armstrong. Well, first, Floyd Landis has alleged that many in the pro peloton, including Lance, turned away from EPO as the preferred doping method in the early 2000's and, instead, reverted to transfusing their blood. The reason for this change was that an effective test for EPO came out. As such, Floyd alleges that Lance, Levi and others transfused their blood around the rest days in the Tour de France. The test for this has been to look for excess mature blood cells relative to immature cells or reticulocytes. Floyd alleges that cyclists got around this test by micro-dosing EPO at night in amounts that would were undetectable by morning. The EPO would lead to new reticulocytes and keep the blood looking normal. This plastic test is a new way to detect blood transfusions.

But, you ask, how can this affect the Lance Armstrong investigation? One very good deterrent to doping that was adopted by pro cycling in the past few years is a requirement that blood and urine samples be maintained for future testing. I recall that at some point in the past decade, cyclists had to agree to this requirement. An article from NY Daily News makes the point that hundreds of Lance Armstrong's urine and blood "specimens are in storage, where they are fair game not only to anti-doping agencies but to" Jeffrey Novitzky and his associates at the FDA who are investigating Lance for fraud. I assume that the same is true for others who Floyd alleges were taking transfusions including Levi Leipheimer, George Hincapie and Dave Zabriskie.

In my opinion, this new test is great news for either Lance or Floyd and horrible news for the other party, depending on who is telling the truth. I believe this new test could be a game changer. In the past, I have said that I didn't think Lance would ever go to jail because he's been able to get the tests that showed he was doping thrown out on technicalities. I've also said that there is so much smoke around him that I don't think he's innocent. 

Assuming this new test is deemed strong evidence of doping and assuming Novitzky gets a hold of several of his specimens, I believe this evidence could resolve any remaining doubts about these allegations. From what I've read, the plastic from these blood bags should still be in the frozen urine and blood. As such, if Novitzky can show a pattern of plasticizers spiking around the rest days to show that Lance was transfusing his blood then Floyd's story will be validated.

I also believe that this evidence could change the tide of belief that he is guilty if enough specimens were tested and showed he had no unusual spikes or amounts of the plastic in his urine or blood. As such, if he is really innocent, he ought to be thrilled at this new test and begging Novitzky to test his urine and blood for these plasticizers. On the other hand, if he is guilty, he ought to be holding a press conference any day now to let the truth prevail.

In the end, this test has serious implications for all those who Floyd alleges were involved in doping. If Levi, George, Dave and others were transfusing their blood they will now want to think twice about how they answer the Grand Jury's questions. There may not be as many urine or blood specimens out there to analyze for these riders as there are for Lance but, this test could lead to time in jail for perjury if they are not telling the truth...

Tuesday, October 5, 2010

More Details on Contador's Doping Tests

The NY Times reported that an anonymous source provided details about Contador's doping tests. It appears that Contador has failed several tests. The initial failure was on the evening of a rest day when a new test for blood doping that looks for a chemical called a plasticizer revealed that the Spaniard had eight times the minimum amount in his urine. This test is new and not yet validated for use. This explains why Contador may have been caught with the test as he may not have anticipated it. However, because it's not yet validated, he may challenge it in court. However, the article quoted the chief of the World Anti-Doping Agency accredited lab in Rome as saying: